| 產(chǎn)品名稱 | JAK2 inhibitor 13 - Sulfonamide 13 |
| 產(chǎn)品貨號 | Axon 1843 CAS [1110502-30-1] MF C17H20N4O2SMW 344.43 Purity: 99% Soluble in DMSO Description Potent and selective Janus Kinase 2 (JAK2) inhibitor; inhibits the activity of both the wild-type JAK2 and the V617F mutant (IC50 = 78 and 206 nM, respectively), with >35-fold selectivity versus JAK3 (IC50 = 2.93 μM) References Certificates Categories Extra info S Antonysamy et al. Fragment-based discovery of JAK-2 inhibitors.?Bioorg. Med. Chem. Lett. 2009, 19(1), 279-282.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics JAK-STAT EC 2.7.10.2 JAK JAK2 inhibitor Chemical name 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide Parent CAS No. [1110502-30-1] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
JAK2 inhibitor 13 - Sulfonamide 13Axon 1843 CAS [1110502-30-1] MF C17H20N4O2S
Description
Potent and selective Janus Kinase 2 (JAK2) inhibitor; inhibits the activity of both the wild-type JAK2 and the V617F mutant (IC50 = 78 and 206 nM, respectively), with >35-fold selectivity versus JAK3 (IC50 = 2.93 μM)
JAK2 inhibitor
Chemical name4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide Parent CAS No.[1110502-30-1] |
| 產(chǎn)品資料 |
