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        產(chǎn)品名稱 CU-T12-9
        產(chǎn)品貨號 Axon 2455 CAS [1821387-73-8] MF C17H13F3N4O2MW 362.31 Purity: 100% Soluble in DMSO Description Selective TLR1/TLR2 agonist (IC50 value 54.4 nM in a competitive binding assay with Pam3CSK4) that facilitates the TLR1/2 heterodimeric complex formation, but not TLR2/6 complex formation. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and inducible NOS. KEYWORDS: CU-T12-9 | Supplier | TLR1/2 agonist | CUT129 | CAS [1821387-73-8] | DNA-RNA | TLR1 | TLR2 | Modulator | Toll-like receptor | immunology | virus | NF-κB | TNF-α | IL-10 | NOS | vaccine adjuvant | antitumor | interleukin | T-cell
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格
        產(chǎn)品品牌 axonmedchem
        產(chǎn)品概述
        產(chǎn)品詳情

        CU-T12-9

        Based on 14 reference(s) in Google Scholar 8 10 14

        Axon 2455

        CAS [1821387-73-8]

        MF C17H13F3N4O2
        MW 362.31

        • Purity: 100%
        • Soluble in DMSO

        CU-T12-9

        Description

        Selective TLR1/TLR2 agonist (IC50 value 54.4 nM in a competitive binding assay with Pam3CSK4) that facilitates the TLR1/2 heterodimeric complex formation, but not TLR2/6 complex formation. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and inducible NOS.

        KEYWORDS: CU-T12-9 | Supplier | TLR1/2 agonist | CUT129 | CAS [1821387-73-8] | DNA-RNA | TLR1 | TLR2 | Modulator | Toll-like receptor | immunology | virus | NF-κB | TNF-α | IL-10 | NOS | vaccine adjuvant | antitumor | interleukin | T-cell

        Selective TLR1/TLR2 agonist that facilitates the TLR1/2 complex formation

        Chemical name

        N-methyl-4-nitro-2-(4-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)aniline

        Parent CAS No.

        [1821387-73-8]

        產(chǎn)品資料
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