| 產(chǎn)品名稱 | CGI 1746 |
| 產(chǎn)品貨號(hào) | Axon 2018 CAS [910232-84-7] MF C34H37N5O4MW 579.69 Purity: 99% Soluble in DMSO Description Potent and highly selective inhibitor of Bruton's tyrosine kinase (Btk) (IC50: 1.9 nM); CGI1746 inhibits B cell signaling and functional effects References Certificates Categories Extra info JA Di Paolo et al. Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis. Nat. Chem. Biol. 2011, 7(1), 41-50.? ? Y Lou et al. Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies. J. Med. Chem. 2012, 55(10), 4539-4350.? ? SL Tamn et al. Targeting the SYK–BTK axis for the treatment of immunological and hematological disorders: Recent progress and therapeutic perspectives. Pharmacol. & Ther. 2013, 138(2), 294-309.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology BTK EC 2.7.10.2 Inhibitor of Bruton's tyrosine kinase (BTK) Chemical name 4-tert-butyl-N-(2-methyl-3-(4-methyl-6-(4-(morpholine-4-carbonyl)phenylamino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide Parent CAS No. [910232-84-7] Order Size Unit Price Stock 2 mg €85.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
CGI 1746Axon 2018 CAS [910232-84-7] MF C34H37N5O4
Description
Potent and highly selective inhibitor of Bruton's tyrosine kinase (Btk) (IC50: 1.9 nM); CGI1746 inhibits B cell signaling and functional effects
Inhibitor of Bruton's tyrosine kinase (BTK)
Chemical name4-tert-butyl-N-(2-methyl-3-(4-methyl-6-(4-(morpholine-4-carbonyl)phenylamino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide Parent CAS No.[910232-84-7] |
| 產(chǎn)品資料 |
