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產(chǎn)品名稱

LFM-A13

產(chǎn)品貨號

Axon 2862 CAS [244240-24-2] MF C11H8Br2N2O2MW 360.00 Purity: 99% Soluble in DMSO Description LFM-A13 is a potent and specific inhibitor of BTK (IC50 value of 2.5 μM). LFM-A13 did not affect the enzymatic activity of other protein tyrosine kinases, including Janus kinases JAK1 and JAK2, Src family kinase HCK, and receptor family tyrosine kinases E. KEYWORDS: LFM-A13 | suppplier | BTK inhibitor | LFM A13 | LFMA13 | CAS [244240-24-2] | B-Cell Transformation | BTK | Inhibitor | Enzymes

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

LFM-A13

Based on 134 reference(s) in Google Scholar 8 10 134

Axon 2862

CAS [244240-24-2]

MF C11H8Br2N2O2
MW 360.00

Purity: 99%
Soluble in DMSO

LFM-A13

Description

LFM-A13 is a potent and specific inhibitor of BTK (IC50 value of 2.5 μM). LFM-A13 did not affect the enzymatic activity of other protein tyrosine kinases, including Janus kinases JAK1 and JAK2, Src family kinase HCK, and receptor family tyrosine kinases E.

S Mahajan et al. Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]. J Biol Chem. 1999 Apr 2;274(14):9587-99.

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology BTK EC 2.7.10.2

Inhibitor of Bruton's tyrosine kinase (BTK)

Chemical name

(Z)-2-Cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide

Parent CAS No.

[244240-24-2]

產(chǎn)品資料

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