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        產(chǎn)品名稱 Pagoclone, (+)- - CI 1043
        產(chǎn)品貨號 Axon 1594 CAS [133737-32-3] MF C23H22ClN3O2MW 407.89 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Subtype selective partial agonist at GABAA receptor, which binds primarily to the α2/α3 subtypes which are responsible for the anti-anxiety effects of these kind of drugs, but has relatively little efficacy at the α1 subtype which produces the sedative and memory loss effects; nonbenzodiazepine anxiolytic References Certificates Categories Extra info JR Atack. The benzodiazepine binding site of GABA(A) receptors as a target for the development of novel anxiolytics. Exp. Opin. Invest. Drugs. 2005, 14(5), 601-618. ? DJ?Nutt. Alcohol alternatives - a goal for psychopharmacology? J. Psychopharmacol. 2006,?20(3), 318–320.? Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation GABA-A Unclassified GABAA-α2 and GABAA-α3 agonist Chemical name 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one Parent CAS No. [133737-32-3] Order Size Unit Price Stock 5 mg €135.00 In Stock
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格
        產(chǎn)品品牌 axonmedchem
        產(chǎn)品概述
        產(chǎn)品詳情

        Pagoclone, (+)- - CI 1043

        Based on 15 reference(s) in Google Scholar 8 10 15

        Axon 1594

        CAS [133737-32-3]

        MF C23H22ClN3O2
        MW 407.89

        • Purity: 99%
        • Optical purity: Optically pure
        • Soluble in DMSO

        Pagoclone, (+)-

        Description

        Subtype selective partial agonist at GABAA receptor, which binds primarily to the α2/α3 subtypes which are responsible for the anti-anxiety effects of these kind of drugs, but has relatively little efficacy at the α1 subtype which produces the sedative and memory loss effects; nonbenzodiazepine anxiolytic
        JR Atack. The benzodiazepine binding site of GABA(A) receptors as a target for the development of novel anxiolytics. Exp. Opin. Invest. Drugs. 2005, 14(5), 601-618.
        ?
        DJ?Nutt. Alcohol alternatives - a goal for psychopharmacology? J. Psychopharmacol. 2006,?20(3), 318–320.?
        GABAA-α2 and GABAA-α3 agonist

        Chemical name

        2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one

        Parent CAS No.

        [133737-32-3]

        產(chǎn)品資料
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