| 產(chǎn)品名稱 | NS 11394 |
| 產(chǎn)品貨號 | Axon 1457 CAS [951650-22-9] MF C23H19N3OMW 353.42 Purity: 99% Soluble in DMSO Description A unique subtype-selective GABAA receptor positive allosteric modulator (PAM); with a subtype selectivity profile at GABAA receptors of α5 > α3 > α2 > α1. Compared with other subtype-selective ligands, NS11394 is unique in having superior efficacy at GABAA-α3 receptors while maintaining low efficacy at GABAA-α1 receptors, which might be attributed for its significantly reduced side effect profile in rat. KEYWORDS:?NS 11394 | supplier | 951650-22-9 | GABAA PAM | NS11394 | GABA-A |?γ-aminobutyric acid | gamma-aminobutyric acid | positive allosteric modulator | agonist |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
NS 11394Axon 1457 CAS [951650-22-9] MF C23H19N3O
DescriptionA unique subtype-selective GABAA receptor positive allosteric modulator (PAM); with a subtype selectivity profile at GABAA receptors of α5 > α3 > α2 > α1. Compared with other subtype-selective ligands, NS11394 is unique in having superior efficacy at GABAA-α3 receptors while maintaining low efficacy at GABAA-α1 receptors, which might be attributed for its significantly reduced side effect profile in rat. KEYWORDS:?NS 11394 | supplier | 951650-22-9 | GABAA PAM | NS11394 | GABA-A |?γ-aminobutyric acid | gamma-aminobutyric acid | positive allosteric modulator | agonist
PAM of GABAA
Chemical name3'-[5-(1-Hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile Parent CAS No.[951650-22-9] |
| 產(chǎn)品資料 |
