| 產(chǎn)品名稱(chēng) | XAV 939 - NVP-XAV 939 |
| 產(chǎn)品貨號(hào) | Axon 1527 CAS [284028-89-3] MF C14H11F3N2OSMW 312.31 Purity: 99% Soluble in DMSO Description Tankyrase (TNKS) inhibitor, with IC50 values to be 11 and 4 nM for TNKS1 and TNKS2 respectively; inhibiting Wnt / β-catenin signaling References Certificates Categories Extra info SM Huang et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signaling. Nature 2009,?461, 614-620.? ? R Nusse. Wnt signaling and stem cell control. Cell Res. 2008,?18, 523-527. ? RT Peterson, Propping up a destructive regime. Nature 2009, 461, 599–600. ? EM Adler. Inhibiting Wnt signaling. Sci. Signal. 2009, 2(91), ec326.? ? CE Meacham et al. In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. Nature Gen. 2009, 41(10), 1131-1137.? Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology Stem Cell Wnt-β-Catenin DNA-damage Response EC 2.4.2.30 TNKS Tankyrase (TNKS) inhibitor Chemical name 2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one Parent CAS No. [284028-89-3] Order Size Unit Price Stock 10 mg €80.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
XAV 939 - NVP-XAV 939Axon 1527 CAS [284028-89-3] MF C14H11F3N2OS
Description
Tankyrase (TNKS) inhibitor, with IC50 values to be 11 and 4 nM for TNKS1 and TNKS2 respectively; inhibiting Wnt / β-catenin signaling
Tankyrase (TNKS) inhibitor
Chemical name2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one Parent CAS No.[284028-89-3] |
| 產(chǎn)品資料 |
