| 產(chǎn)品名稱 | AZD 6244 - ARRY 142886 | Selumetinib |
| 產(chǎn)品貨號(hào) | Axon 1516 CAS [606143-52-6] MF C17H15BrClFN4O3MW 457.68 Purity: 99% Soluble in DMSO Description An orally active, highly potent and selective inhibitor of MEK 1/2 that has shown tumor-suppressive activity in a wide range of preclinical models. IC50 value to be 14 nM against purified MEK1 References Certificates Categories Extra info TC Yeh et al. Biological Characterization of ARRY-142886 (AZD6244), a Potent, Highly Selective Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor. Clin. Cancer Res. 2007, 13, 1576-1583.? ? BR Davies et al. AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases. Mol. Cancer Ther. 2007, 6(8), 2209-2019.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell MAPK EC 2.7.12.2 MEK MEK1 and MEK2 inhibitor Chemical name 5-(4-bromo-2-chlorophenylamino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide Parent CAS No. [606143-52-6] Order Size Unit Price Stock 5 mg €70.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
AZD 6244 - ARRY 142886 | SelumetinibAxon 1516 CAS [606143-52-6] MF C17H15BrClFN4O3
Description
An orally active, highly potent and selective inhibitor of MEK 1/2 that has shown tumor-suppressive activity in a wide range of preclinical models. IC50 value to be 14 nM against purified MEK1
MEK1 and MEK2 inhibitor
Chemical name5-(4-bromo-2-chlorophenylamino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide Parent CAS No.[606143-52-6] |
| 產(chǎn)品資料 |
