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產品名稱

Tariquidar - XR 9576

產品貨號

Axon 1960 CAS [206873-63-4] MF C38H38N4O6MW 646.73 Purity: 98% Soluble in DMSO Description Potent and specific inhibitor of P-glycoprotein (P-gp, ABCB1); also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2). KEYWORDS:?Tariquidar | supplier | P-gp inhibitor | XR 9576 | XR9576 | CAS [206873-63-4] | P-glycoprotein | PGP | breast cancer | BCRP | ABCG2 | multidrug resistance | efflux pump

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

產品品牌

axonmedchem

產品概述

產品詳情

Tariquidar - XR 9576

Based on 469 publications in PubMed 10 10 469

Axon 1960

CAS [206873-63-4]

MF C38H38N4O6
MW 646.73

Purity: 98%
Soluble in DMSO

Tariquidar

Description

Potent and specific inhibitor of P-glycoprotein (P-gp, ABCB1); also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2).

KEYWORDS:?Tariquidar | supplier | P-gp inhibitor | XR 9576 | XR9576 | CAS [206873-63-4] | P-glycoprotein | PGP | breast cancer | BCRP | ABCG2 | multidrug resistance | efflux pump

E Fox, SE Bates. Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor. Expert Rev. Anticancer Ther. 2007, 7(4), 447-459.?

?

I. Leitner et al. The third-generation P-glycoprotein inhibitor tariquidar may overcome bacterial multidrug resistance by increasing intracellular drug concentration. J. Antimicrob. Chemother. 2011, 66(4),? 834-839.?

?

P Kannan et al. The “Specific” P-Glycoprotein Inhibitor Tariquidar Is Also a Substrate and an Inhibitor for Breast Cancer Resistance Protein (BCRP/ABCG2). ACS Chem. Neurosci., 2011, 2(2), 82–89.?

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology CNS P-glycoprotein Unclassified

Inhibitor of P-glycoprotein (P-gp, ABCB1)

Chemical name

N-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenylcarbamoyl)-4,5-dimethoxyphenyl)quinoline-3-carboxamide

Parent CAS No.

[206873-63-4]

產品資料

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