| 產(chǎn)品名稱 | FR 180204 |
| 產(chǎn)品貨號 | Axon 1694 CAS [865362-74-9] MF C18H13N7MW 327.34 Purity: 99% Soluble in DMSO Description Selective, cell permeable and ATP-competitive ERK inhibitor; 30-fold selective on ERK over p38α MAPK; FR180204 was shown to inhibit ERK1 (Ki=0.31μM), ERK2 (Ki=0.14 μM) and TGFβ-induced AP-1 activation References Certificates Categories Extra info M Ohori et al. Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex. Biochem Biophys Res Commun. 2005, 336(1), 357-363. ? M Ohori. ERK inhibitors as a potential new therapy for rheumatoid arthritis. Drug News Perspect. 2008, 21(5), 245-250. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Transcription Factors MAPK PI3K-Akt-mTOR EC 2.7.11.24 ERK ERK inhibitor; AP-1 inhibitor Chemical name 3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-7H-pyrazolo[3,4-c]pyridazin-5-amine Parent CAS No. [865362-74-9] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
FR 180204Axon 1694 CAS [865362-74-9] MF C18H13N7
Description
Selective, cell permeable and ATP-competitive ERK inhibitor; 30-fold selective on ERK over p38α MAPK; FR180204 was shown to inhibit ERK1 (Ki=0.31μM), ERK2 (Ki=0.14 μM) and TGFβ-induced AP-1 activation
ERK inhibitor; AP-1 inhibitor
Chemical name3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-7H-pyrazolo[3,4-c]pyridazin-5-amine Parent CAS No.[865362-74-9] |
| 產(chǎn)品資料 |
