| 產(chǎn)品名稱 | ML 210 - CID 49766530 |
| 產(chǎn)品貨號 | Axon 2017 CAS [1360705-96-9] MF C22H20Cl2N4O4MW 475.32 Purity: 100% Soluble in DMSO Description Chemical probe that selectively kills cells induced to express mutant RAS; more specifically, ML210 is a HRAS synthetic lethal compound with nanomolar potencies against two HRASG12V expressing cell lines and 4-fold selectivity against two control cell lines not expressing HRASG12V References Certificates Categories Extra info JA Bittker et al. Screen for RAS-Selective Lethal Compounds and VDAC Ligands - Probe 2. Probe Reports NIH Mol. Lib. Program. PMID: 22834036.? ? M We?wer et al. Development of small-molecule probes that selectively kill cells induced to express mutant RAS. Bioorg. Med. Chem. Lett. 2012, 22(4), 1822-1826.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology MAPK EC 3.6.5.2 HRAS Chemical probe that selectively kills cells induced to express mutant RAS Chemical name (4-(bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone Parent CAS No. [1360705-96-9] Order Size Unit Price Stock 10 mg €115.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
ML 210 - CID 49766530Axon 2017 CAS [1360705-96-9] MF C22H20Cl2N4O4
Description
Chemical probe that selectively kills cells induced to express mutant RAS; more specifically, ML210 is a HRAS synthetic lethal compound with nanomolar potencies against two HRASG12V expressing cell lines and 4-fold selectivity against two control cell lines not expressing HRASG12V
Chemical probe that selectively kills cells induced to express mutant RAS
Chemical name(4-(bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone Parent CAS No.[1360705-96-9] |
| 產(chǎn)品資料 |
