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產(chǎn)品名稱

SR 3576

產(chǎn)品貨號

Axon 2365 CAS [1164153-22-3] MF C27H27N5O5MW 501.53 Purity: 99% Soluble in DMSO Description Very potent JNK3 inhibitor (IC50 value 7 nM) with >2800-fold selectivity over p38 (p38 IC50 value >20 μm) and a cell-based potency of ca. 1 μM. References Certificates Categories Extra info T. Kamenecka et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J. Biol. Chem. 2009, 284, 12853-12861. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation MAPK (JNK) p53-Tumor Suppression NF-κB MAPK EC 2.7.11.24 Very potent JNK3 inhibitor with >2800-fold selectivity over p38 Chemical name 3-(4-(3-m-tolylureido)-1H-pyrazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide Parent CAS No. [1164153-22-3] Order Size Unit Price Stock 10 mg €135.00 In Stock

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

SR 3576

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2365

CAS [1164153-22-3]

MF C27H27N5O5
MW 501.53

Purity: 99%
Soluble in DMSO

SR 3576

Description

Very potent JNK3 inhibitor (IC50 value 7 nM) with >2800-fold selectivity over p38 (p38 IC50 value >20 μm) and a cell-based potency of ca. 1 μM.

T. Kamenecka et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J. Biol. Chem. 2009, 284, 12853-12861.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation MAPK (JNK) p53-Tumor Suppression NF-κB MAPK EC 2.7.11.24

Very potent JNK3 inhibitor with >2800-fold selectivity over p38

Chemical name

3-(4-(3-m-tolylureido)-1H-pyrazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide

Parent CAS No.

[1164153-22-3]

產(chǎn)品資料

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