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產(chǎn)品名稱

EPZ 015666 - GSK 3235025

產(chǎn)品貨號

Axon 2831 CAS [1616391-65-1] MF C20H25N5O3MW 383.44 Purity: 99% Optical purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description EPZ 015666 (GSK 3235025) is a potent, selective and orally available inhibitor of PRMT5 (IC50 value of 22 nM). EPZ 015666 exhibits antiproliferative effects in both in vitro and in vivo models of MCL. KEYWORDS: EPZ015666 | supplier | PRMT5 inhibitor | GSK3235025 | EPZ-015666 | EPZ 015666 | GSK-3235025 | GSK 3235025 | CAS [1616391-65-1] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

EPZ 015666 - GSK 3235025

Based on 6 reference(s) in Google Scholar 8 10 6

Axon 2831

CAS [1616391-65-1]

MF C20H25N5O3
MW 383.44

Purity: 99%
Optical purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

EPZ 015666

Description

EPZ 015666 (GSK 3235025) is a potent, selective and orally available inhibitor of PRMT5 (IC50 value of 22 nM). EPZ 015666 exhibits antiproliferative effects in both in vitro and in vivo models of MCL.

KEYWORDS: EPZ015666 | supplier | PRMT5 inhibitor | GSK3235025 | EPZ-015666 | EPZ 015666 | GSK-3235025 | GSK 3235025 | CAS [1616391-65-1] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes

E Chan-Penebre et al. A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat Chem Biol. 2015 Jun;11(6):432-7.

Certificate of Analysis
Material Safety Data Sheet

Cell Cycle Regulation Cell Signaling & Oncology Epigenetics Endocrinology EC 2.1.1.125 PRMT

Potent, selective and orally available inhibitor of PRMT5

Chemical name

(S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide

Parent CAS No.

[1616391-65-1]

產(chǎn)品資料

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