| 產(chǎn)品名稱(chēng) | CMP5 |
| 產(chǎn)品貨號(hào) | Axon 2709 CAS [1030021-40-9] MF C20H22N3.HClMW 351.87 Purity: 99% Soluble in water and DMSO Description CMP5 is a selective PRMT5 inhibitor that blocked EBV-driven B-lymphocyte transformation and survival while leaving normal B cells unaffected. Also CMP5 inhibited Th1 cell proliferation (IC50 value 3.7 μM) more potently than Th2 cell proliferation (IC50 value 9.2 μM). In vivo, PRMT5 blockade efficiently suppressed recall T cell responses and reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Also the more potent and bioavailable derivative HLCL65 hydrochloride is available (Axon 2710). |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
CMP5Axon 2709 CAS [1030021-40-9] MF C20H22N3.HCl
DescriptionCMP5 is a selective PRMT5 inhibitor that blocked EBV-driven B-lymphocyte transformation and survival while leaving normal B cells unaffected. Also CMP5 inhibited Th1 cell proliferation (IC50 value 3.7 μM) more potently than Th2 cell proliferation (IC50 value 9.2 μM). In vivo, PRMT5 blockade efficiently suppressed recall T cell responses and reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Also the more potent and bioavailable derivative HLCL65 hydrochloride is available (Axon 2710). KEYWORDS: CMP5 | supplier | PRMT5 inhibitor | CMP 5 | CMP-5 | CAS [1030021-40-9] | [880813-42-3] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes
Inhibitor of PRMT5
Chemical name1-(9-Ethyl-9H-carbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine hydrochloride Parent CAS No.[880813-42-3] |
| 產(chǎn)品資料 |
