| 產(chǎn)品名稱 | HLCL65 hydrochloride |
| 產(chǎn)品貨號(hào) | Axon 2710 CAS [N.A.] MF C23H23BrN2O.HClMW 459.81 Purity: 99% Soluble in DMSO Description HLCL65 is a highly selective small molecule PRMT5 inhibitor. HLCL65 inhibited Th1 cell proliferation (IC50 value 1.1 μM) more potently than Th2 cell proliferation (IC50 value 4 μM). In vivo, PRMT5 blockade efficiently suppressed recall T cell responses and reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. HLCL65 is a more potent and bioavailable derivative of CMP5 (Axon 2709). KEYWORDS: HLCL65 hydrochloride | supplier | PRMT5 inhibitor | HLCL-65 | HLCL 65 | CAS [1627865-11-5] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
HLCL65 hydrochlorideAxon 2710 CAS [N.A.] MF C23H23BrN2O.HCl
DescriptionHLCL65 is a highly selective small molecule PRMT5 inhibitor. HLCL65 inhibited Th1 cell proliferation (IC50 value 1.1 μM) more potently than Th2 cell proliferation (IC50 value 4 μM). In vivo, PRMT5 blockade efficiently suppressed recall T cell responses and reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. HLCL65 is a more potent and bioavailable derivative of CMP5 (Axon 2709). KEYWORDS: HLCL65 hydrochloride | supplier | PRMT5 inhibitor | HLCL-65 | HLCL 65 | CAS [1627865-11-5] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes
Inhibitor of PRMT5
Chemical name1-(6-Bromo-9-ethyl-9H-carbazol-3-yl)-N-(2-methoxybenzyl)methanamine hydrochloride Parent CAS No.[1627865-11-5] |
| 產(chǎn)品資料 |
