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產(chǎn)品名稱

UNC 0638

產(chǎn)品貨號

Axon 1889 CAS [1255580-76-7] MF C30H47N5O2MW 509.73 Purity: 98% Soluble in DMSO Description Potent and selective G9a (EHMT2)/GLP (EHMT1) inhibitor (G9a IC50: <15 nM; GLP IC50: 19 nM); chemical probe for G9a and GLP methyltransferase inhibition in cells References Certificates Categories Extra info M Vedadi et al. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat. Chem. Biol. 2011, 7(8), 566-574. ? F Liu et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J. Med. Chem. 2011, 54(17), 6139-6150. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics EC 2.1.1.43 HMTase Inhibitor of G9a (EHMT2)/GLP (EHMT1) Chemical name 2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine Parent CAS No. [1255580-76-7] Order Size Unit Price Stock 2 mg €85.00 In Stock

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現(xiàn)貨詢價(jià)，電話：010-67529703

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產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

UNC 0638

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1889

CAS [1255580-76-7]

MF C30H47N5O2
MW 509.73

Purity: 98%
Soluble in DMSO

UNC 0638

Description

Potent and selective G9a (EHMT2)/GLP (EHMT1) inhibitor (G9a IC50: <15 nM; GLP IC50: 19 nM); chemical probe for G9a and GLP methyltransferase inhibition in cells

M Vedadi et al. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat. Chem. Biol. 2011, 7(8), 566-574.

F Liu et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J. Med. Chem. 2011, 54(17), 6139-6150.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics EC 2.1.1.43 HMTase

Inhibitor of G9a (EHMT2)/GLP (EHMT1)

Chemical name

2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine

Parent CAS No.

[1255580-76-7]

產(chǎn)品資料

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