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產品名稱

UNC 0646

產品貨號

Axon 1840 CAS [1320288-17-2] MF C36H59N7O2MW 621.90 Purity: 99% Soluble in DMSO Description Very potent and selective G9a/GLP protein lysine methyltransferase inhibitor (G9a IC50: 6 nM; GLP IC50: 15 nM); with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity References Certificates Categories Extra info F Liu et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J. Med. Chem. 2011, 54(17), 6139-6150.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics EC 2.1.1.43 HMTase Inhibitor of G9a/GLP Histone Lysine Methyltransferase Chemical name N-(1-cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine Parent CAS No. [1320288-17-2] Order Size Unit Price Stock 5 mg €99.00 In Stock

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

產品品牌

axonmedchem

產品概述

產品詳情

UNC 0646

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1840

CAS [1320288-17-2]

MF C36H59N7O2
MW 621.90

Purity: 99%
Soluble in DMSO

UNC 0646

Description

Very potent and selective G9a/GLP protein lysine methyltransferase inhibitor (G9a IC50: 6 nM; GLP IC50: 15 nM); with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity

F Liu et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J. Med. Chem. 2011, 54(17), 6139-6150.?

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics EC 2.1.1.43 HMTase

Inhibitor of G9a/GLP Histone Lysine Methyltransferase

Chemical name

N-(1-cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine

Parent CAS No.

[1320288-17-2]

產品資料

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