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產(chǎn)品名稱(chēng)

AM 36 dihydrochloride - CNSB002

產(chǎn)品貨號(hào)

Axon 1113 CAS [199467-52-2] MF C27H39ClN2O2.2HClMW 531.99 Purity: 98% Moderately soluble in water Description Na+ channel blocker; neuroprotective agent. KEYWORDS: AM 36 dihydrochloride | supplier | Na+ channel Blocker | CNSB002 | AM36 |CAS[199467-52-2] | Sodium | Blocker | Ion Channels | Nav1.3 | Nav1.7 | Nav1.8 | neuropathic pain | analgesic | neuroprotective |ROS

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

AM 36 dihydrochloride - CNSB002

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1113

CAS [199467-52-2]

MF C27H39ClN2O2.2HCl
MW 531.99

Purity: 98%
Moderately soluble in water

AM 36 dihydrochloride

Description

Na+ channel blocker; neuroprotective agent.

KEYWORDS: AM 36 dihydrochloride | supplier | Na+ channel Blocker | CNSB002 | AM36 |CAS[199467-52-2] | Sodium | Blocker | Ion Channels | Nav1.3 | Nav1.7 | Nav1.8 | neuropathic pain | analgesic | neuroprotective |ROS

J. K. Callaway et al.?Delayed Treatment With AM-36, a Novel Neuroprotective Agent, Reduces Neuronal Damage After Endothelin-1–Induced Middle Cerebral Artery Occlusion in Conscious Rats.?Stroke. 1999, 30, 2704-2712.

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J. K?Callaway et al. Incorporation of sodium channel blocking and free radical scavenging activities into a single drug, AM-36, results in profound inhibition of neuronal apoptosis. Br. J. Pharmacol. 2001, 132, 1691–1698.

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A. Kolosov et al. Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain. Pain Med. 2010 Jan;11(1):106-18.

Certificate of Analysis
Material Safety Data Sheet

CNS Pain & Inflammation Nav1.7 Unclassified Nav1.2 Nav1.3

Na+ channel blocker

Chemical name

2,6-Di-tert-butyl-4-{4-[2-(4-chloro-phenyl)-2-hydroxy-ethyl]-piperazin-1-ylmethyl}-phenol dihydrochloride

Parent CAS No.

[199467-52-2]

產(chǎn)品資料

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