| 產(chǎn)品名稱 | Salermide |
| 產(chǎn)品貨號(hào) | Axon 2704 CAS [1105698-15-4] MF C26H22N2O2MW 394.47 Purity: 99% Soluble in DMSO Description Salermide is a reverse amide with a potent in vitro inhibitory effect on Sirt1 and Sirt2. Salermide was well tolerated by mice at concentrations up to 100 μM and prompted tumour-specific cell death in a wide range of human cancer cell lines. It induces massive apoptosis in cancer but not in non-transformed cultured cells. The apoptotic effect of Salermide is in part because of the reactivation of proapoptotic genes that are epigenetically repressed by Sirt1 exclusively in cancer cells. KEYWORDS: Salermide | supplier | SIRT inhibitor | CAS [1105698-15-4] | Histone | SIRT | Inhibitor | Enzymes |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
SalermideAxon 2704 CAS [1105698-15-4] MF C26H22N2O2
DescriptionSalermide is a reverse amide with a potent in vitro inhibitory effect on Sirt1 and Sirt2. Salermide was well tolerated by mice at concentrations up to 100 μM and prompted tumour-specific cell death in a wide range of human cancer cell lines. It induces massive apoptosis in cancer but not in non-transformed cultured cells. The apoptotic effect of Salermide is in part because of the reactivation of proapoptotic genes that are epigenetically repressed by Sirt1 exclusively in cancer cells. KEYWORDS: Salermide | supplier | SIRT inhibitor | CAS [1105698-15-4] | Histone | SIRT | Inhibitor | Enzymes
Potent inhibitor of SIRT1 and SIRT2
Chemical nameN-(3-((2-Hydroxynaphthalen-1-yl)methyleneamino)phenyl)-2-phenylpropanamide Parent CAS No.[1105698-15-4] |
| 產(chǎn)品資料 |
