| 產(chǎn)品名稱 | BAY 58-2667 hydrochloride - Cinaciguat hydrochloride |
| 產(chǎn)品貨號 | Axon 2172 CAS [646995-35-9] MF C36H39NO5.HClMW 602.16 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Potent nitric oxide (NO)-independent soluble guanylyl cyclase (sGC) activator with haemodynamic effect similar to that of nitroglycerin (Ki value 6-8 nM in competition binding studies). Acts specifically on oxidized/haem-free sGC by binding to the enzyme's haem pocket and mimicking the nitric-oxide-bound haem group. BAY 58-2667 is in clinical development for the treatment of acute decompensated heart failure (ADHF). KEYWORDS:?BAY 58-2667 hydrochloride | supplier | sGC activator | Cinaciguat hydrochloride | BAY58-2667 | CAS [646995-35-9] | [329773-35-5] | GTP | sGC | soluble | guanylyl cyclase | NO | nitric oxide | heart failure | cardiac | ADHF |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
BAY 58-2667 hydrochloride - Cinaciguat hydrochlorideAxon 2172 CAS [646995-35-9] MF C36H39NO5.HCl
DescriptionPotent nitric oxide (NO)-independent soluble guanylyl cyclase (sGC) activator with haemodynamic effect similar to that of nitroglycerin (Ki value 6-8 nM in competition binding studies). Acts specifically on oxidized/haem-free sGC by binding to the enzyme's haem pocket and mimicking the nitric-oxide-bound haem group. BAY 58-2667 is in clinical development for the treatment of acute decompensated heart failure (ADHF). KEYWORDS:?BAY 58-2667 hydrochloride | supplier | sGC activator | Cinaciguat hydrochloride | BAY58-2667 | CAS [646995-35-9] | [329773-35-5] | GTP | sGC | soluble | guanylyl cyclase | NO | nitric oxide | heart failure | cardiac | ADHF
Soluble, potent nitric oxide-independent guanylyl cyclase (sGC) activator
Chemical name4-(((4-carboxybutyl)(2-(4-phenethylbenzyloxy)phenethyl)amino)methyl)benzoic acid hydrochloride Parent CAS No.[329773-35-5] |
| 產(chǎn)品資料 |
