| 產(chǎn)品名稱 | Blebbistatin, (±)- |
| 產(chǎn)品貨號(hào) | Axon 2718 CAS [674289-55-5] MF C18H16N2O2MW 292.33 Purity: 99% Soluble in DMSO Description Blebbistatin is a potent and specific inhibitor of the motor functions of class II myosins (IC50 values of 6.47, 3.58, 2.30 and 1.57 μM for inhibiting actin-activated ATPase activities of SmM, NM2a, NM2b and NM2c, respectively). Blebbistatin inhibited contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Moreover, Blebbistatin inhibited both the ATPase and gliding motility activities of human platelet nonmuscle myosin II without inhibiting myosin light chain kinase. KEYWORDS: (±)-Blebbistatin | Myosin II inhibitor | Blebbistatin | CAS [674289-55-5] | ATP | ATPase (myosin) | Inhibitor | Enzymes |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
Blebbistatin, (±)-Axon 2718 CAS [674289-55-5] MF C18H16N2O2
DescriptionBlebbistatin is a potent and specific inhibitor of the motor functions of class II myosins (IC50 values of 6.47, 3.58, 2.30 and 1.57 μM for inhibiting actin-activated ATPase activities of SmM, NM2a, NM2b and NM2c, respectively). Blebbistatin inhibited contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Moreover, Blebbistatin inhibited both the ATPase and gliding motility activities of human platelet nonmuscle myosin II without inhibiting myosin light chain kinase. KEYWORDS: (±)-Blebbistatin | Myosin II inhibitor | Blebbistatin | CAS [674289-55-5] | ATP | ATPase (myosin) | Inhibitor | Enzymes
Potent and specific inhibitor of class II myosins
Chemical name3a-Hydroxy-6-methyl-1-phenyl-3,3a-dihydro-1H-pyrrolo[2,3-b]quinolin-4(2H)-one Parent CAS No.[674289-55-5] |
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