| 產(chǎn)品名稱 | KU 55933 |
| 產(chǎn)品貨號(hào) | Axon 1367 CAS [587871-26-9] MF C21H17NO3S2MW 395.49 Purity: 99% Soluble in DMSO Description Potent, ATP-competitive and selective ATM?inhibitor (Ki = 2.2 nM, IC50 =?13 nM) References Certificates Categories Extra info I Hickson et al. Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM. Cancer Res. 2004, 64, 9152. ? A Lau et al. Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase. Nat. Cell Biol. 2005,?7, 493-500. ? Y Li and DQ Yang. The ATM Inhibitor KU-55933 Suppresses Cell Proliferation and Induces Apoptosis by Blocking Akt In Cancer Cells with Overactivated Akt. Mol. Cancer Ther. 2010, 9, 113. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology ATM p53-Tumor Suppression PI3K-Akt-mTOR DNA-damage Response EC 2.7.11.1 ATM inhibitor Chemical name 2-Morpholin-4-yl-6-thianthren-1-yl-pyran-4-one Parent CAS No. [587871-26-9] Order Size Unit Price Stock 10 mg €125.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià),電話:010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
KU 55933Axon 1367 CAS [587871-26-9] MF C21H17NO3S2
Description
Potent, ATP-competitive and selective ATM?inhibitor (Ki = 2.2 nM, IC50 =?13 nM)
ATM inhibitor
Chemical name2-Morpholin-4-yl-6-thianthren-1-yl-pyran-4-one Parent CAS No.[587871-26-9] |
| 產(chǎn)品資料 |