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產(chǎn)品名稱

25CN-NBOH hydrochloride - NBOH-2C-CN hydrochloride

產(chǎn)品貨號

Axon 2811 CAS [1539266-32-4] MF C18H20N2O3.HClMW 348.82 Purity: 98% Soluble in water and DMSO Description 25CN-NBOH is a highly selective and brain penetrant 5-HT2A receptor agonist (Ki value of 1.3 nM; EC50 value of 2.1 nM). Moreover, 25CN-NBOH was behaviorally active in two mouse models of hallucinogenic effects. KEYWORDS: 25CN-NBOH hydrochloride | supplier | 5-HT2A agonist? | NBOH-2C-CN hydrochloride | 25CN NBOH hydrochloride | 25CNNBOH hydrochloride | CAS [1539266-32-4] | [1391489-32-9] | Serotonin | 5-HT2A | Agonist | Receptors

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

25CN-NBOH hydrochloride - NBOH-2C-CN hydrochloride

Based on 5 reference(s) in Google Scholar 8 10 5

Axon 2811

CAS [1539266-32-4]

MF C18H20N2O3.HCl
MW 348.82

Purity: 98%
Soluble in water and DMSO

25CN-NBOH hydrochloride

Description

25CN-NBOH is a highly selective and brain penetrant 5-HT2A receptor agonist (Ki value of 1.3 nM; EC50 value of 2.1 nM). Moreover, 25CN-NBOH was behaviorally active in two mouse models of hallucinogenic effects.

M Hansen et al. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. ACS Chem Neurosci. 2014 Mar 19;5(3):243-9.

WE Fantegrossi et al. Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH),?a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT?A receptors, in mice.?Psychopharmacology (Berl). 2015 Mar;232(6):1039-47.

AA Jensen et al. Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH),?a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist.?J Pharmacol Exp Ther. 2017 Jun;361(3):441-453.

Certificate of Analysis
Material Safety Data Sheet

CNS 5-HT2A A17

Selective brain penetrant 5-HT2A receptor agonist

Chemical name

4-(2-(2-Hydroxybenzylamino)ethyl)-2,5-dimethoxybenzonitrile hydrochloride

Parent CAS No.

[1391489-32-9]

產(chǎn)品資料

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