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產(chǎn)品名稱

Fluphenazine decanoate dihydrochloride - Prolixin Decanoate dihydrochloride

產(chǎn)品貨號(hào)

Axon 2127 CAS [2376-65-0] MF C32H44F3N3O2S.2HClMW 664.69 Purity: 99% Soluble in DMSO Description Fluphenazine (available after slow hydrolysis in vivo of the parent molecule) is a potent antipsychotic (Ki values 0.2 nM, 0.11 nM, and 2.0nM for D2, D3, and 5-HT2 receptors, respectively). Fluphenazine exhibits considerable affintiy for 5-HT6 and 5-HT7 receptors (Ki values 15.8nM and 7.9 nM, respectively) as well. References Certificates Categories Extra info H.L. Yale et al. Esters of 4-{3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl}-1-piperazine?thanol as long-acting tranquilizing agents. Synthesis of... J. Med. Chem., 1963, 6, 347-350. ? P. Seeman et al. Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Mol. Psychiatry. 1998, 3, 123-134. ? B.L. Roth et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J. Pharmacol. Exp. Ther. 1994, 268, 1403-1410. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation Endocrinology D2 D3 A17 Antipsychotic with high affinity for dopamine and serotonin receptors Chemical name 2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl decanoate dihydrochloride Parent CAS No. [5002-47-1] Order Size Unit Price Stock 10 mg €75.00 In Stock

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axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Fluphenazine decanoate dihydrochloride - Prolixin Decanoate dihydrochloride

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2127

CAS [2376-65-0]

MF C32H44F3N3O2S.2HCl
MW 664.69

Purity: 99%
Soluble in DMSO

Fluphenazine decanoate dihydrochloride

Description

Fluphenazine (available after slow hydrolysis in vivo of the parent molecule) is a potent antipsychotic (Ki values 0.2 nM, 0.11 nM, and 2.0nM for D2, D3, and 5-HT2 receptors, respectively). Fluphenazine exhibits considerable affintiy for 5-HT6 and 5-HT7 receptors (Ki values 15.8nM and 7.9 nM, respectively) as well.

H.L. Yale et al. Esters of 4-{3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl}-1-piperazine?thanol as long-acting tranquilizing agents. Synthesis of... J. Med. Chem., 1963, 6, 347-350.

P. Seeman et al. Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Mol. Psychiatry. 1998, 3, 123-134.

B.L. Roth et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J. Pharmacol. Exp. Ther. 1994, 268, 1403-1410.

Certificate of Analysis
Material Safety Data Sheet

CNS Pain & Inflammation Endocrinology D2 D3 A17

Antipsychotic with high affinity for dopamine and serotonin receptors

Chemical name

2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl decanoate dihydrochloride

Parent CAS No.

[5002-47-1]

產(chǎn)品資料

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