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產(chǎn)品名稱

Hydroxybuspirone hydrochloride, 6- - BMS 528215 hydrochloride | 6OHB | 6-OH-Bu

產(chǎn)品貨號

Axon 1996 CAS [N.A.] MF C21H31N5O3.HClMW 437.96 Purity: 98% Soluble in water and DMSO Description A major active metabolite of Buspirone (Axon 1995), a 5-HT1A partial agonist; with improved bioavailability (19%) compared with that for buspirone (1.4%); contributes significantly to the clinical efficacy of buspirone as an anxiolytic agent References Certificates Categories Extra info H Wong et al. 6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats. Drug Metab. Dispos. 2007, 35(8), 1387-1392.? ? RC Dockens et al. Pharmacokinetics of 6-hydroxybuspirone and its enantiomers administered individually or following buspirone administration in humans. Biopharm. Drug Dispos. 2007, 28(7), 393-402.? ? SJ Nicholson et al. Development of oral extended release formulations of 6-hydroxybuspirone. Biopharm. Drug Dispos. 2012, 33(9), 522-535.? Certificate of Analysis Material Safety Data Sheet CNS 5-HT1A A19 5-HT1A partial agonist Chemical name 6-hydroxy-8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione hydrochloride Parent CAS No. [125481-61-0] Order Size Unit Price Stock 5 mg €135.00 In Stock

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Hydroxybuspirone hydrochloride, 6- - BMS 528215 hydrochloride | 6OHB | 6-OH-Bu

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1996

CAS [N.A.]

MF C21H31N5O3.HCl
MW 437.96

Purity: 98%
Soluble in water and DMSO

Hydroxybuspirone hydrochloride, 6-

Description

A major active metabolite of Buspirone (Axon 1995), a 5-HT1A partial agonist; with improved bioavailability (19%) compared with that for buspirone (1.4%); contributes significantly to the clinical efficacy of buspirone as an anxiolytic agent

H Wong et al. 6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats. Drug Metab. Dispos. 2007, 35(8), 1387-1392.?

RC Dockens et al. Pharmacokinetics of 6-hydroxybuspirone and its enantiomers administered individually or following buspirone administration in humans. Biopharm. Drug Dispos. 2007, 28(7), 393-402.?

SJ Nicholson et al. Development of oral extended release formulations of 6-hydroxybuspirone. Biopharm. Drug Dispos. 2012, 33(9), 522-535.?

Certificate of Analysis
Material Safety Data Sheet

CNS 5-HT1A A19

5-HT1A partial agonist

Chemical name

6-hydroxy-8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione hydrochloride

Parent CAS No.

[125481-61-0]

產(chǎn)品資料

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