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產(chǎn)品名稱

GMC 1-165

產(chǎn)品貨號

Axon 1152 CAS [156632-07-4] MF C18H20N4OMW 308.38 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Analogue of clozapine (Axon 1146); devoid of DA affinities but with affinities at 5-HT2A/2C and hM1 receptors. Another analogue and metabolite of cloazapine, with 8-hydroxy moiety,?GMC1-116 (

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

GMC 1-165

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1152

CAS [156632-07-4]

MF C18H20N4O
MW 308.38

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

GMC 1-165

Description

Analogue of clozapine (Axon 1146); devoid of DA affinities but with affinities at 5-HT2A/2C and hM1 receptors.

Another analogue and metabolite of cloazapine, with 8-hydroxy moiety,?GMC1-116 (Axon 1151), is also available.

KEYWORDS: GMC 1-165 | supplier | Clozapine analogue | GMC1-165 | GMC1165 | CAS [156632-07-4] | Serotonin | 5-HT2A | 5-HT2C | CHRM1 | Agonist | Receptors

Liao, Y. et al. Synthesis and pharmacological evaluation of triflate-substituted analogues of Clozapine: Identification of a novel atypical neuroleptic.?J. Med. Chem. 1997,?40, 4146-4153.

Y. Liao et al. New sulfonyloxy piperazinyldibenzazapines as potential atypical antipsychotics: chemistry and pharmacological evaluation.?J. Med. Chem. 1999,42, 2235-2244.

Certificate of Analysis
Material Safety Data Sheet

CNS 5-HT2A 5-HT2C CHRM1

Clozapine analog with 5-HT2A and M1 affinity, devoid of D1/D2 affinities

Chemical name

11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-ol

Parent CAS No.

[156632-07-4]

產(chǎn)品資料

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