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產(chǎn)品名稱

WAY 100635 hydrochloride

產(chǎn)品貨號

Axon 1086 CAS [146714-97-8] MF C25H34N4O2.xHClMW 459.02 Purity: 99% Soluble in water and DMSO Description Prototypical 5-HT1A receptor antagonist with D4 agonist activity (Ki values 2.2 nM, 6260 nM, 24 nM, >10,000 nM, 20 nM, 322 nM, and 16 nM for 5-HT1A, 5-HT2A, 5-HT2B, 5-HT7, α1A, α1B, and D4, respectively). The maleate salt of WAY 100635 is available as well (Axon 2424). Prime Source Information

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

WAY 100635 hydrochloride

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1086

CAS [146714-97-8]

MF C25H34N4O2.xHCl
MW 459.02

Purity: 99%
Soluble in water and DMSO

WAY 100635 hydrochloride

Description

Prototypical 5-HT1A receptor antagonist with D4 agonist activity (Ki values 2.2 nM, 6260 nM, 24 nM, >10,000 nM, 20 nM, 322 nM, and 16 nM for 5-HT1A, 5-HT2A, 5-HT2B, 5-HT7, α1A, α1B, and D4, respectively).

The maleate salt of WAY 100635 is available as well (Axon 2424).

Prime Source Information:
The molecule of WAY 100635 contains multiple basic nitrogens, which could form 1 to 3 eq HCl salt of WAY 100635. Its accurate salt form has been determined by microanalysis and is specified on the certificate of analysis (COA) of every batch of our samples

B.R. Chemel et al. WAY-100635 is a potent dopamine D4 receptor agonist. Psychopharmacology (Berl). 2006 Oct;188(2):244-51.

EA Forster?et al.?A pharmacological profile of the selective silent 5-HT1A receptor antagonist WAY-100635. Eur. J. Pharmacol. 1995, 281, 81-88.?

Certificate of Analysis
Material Safety Data Sheet

CNS 5-HT1A 5-HT2 D4 Adrenoceptor α1 A17

5-HT1A antagonist

Chemical name

Cyclohexanecarboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyridin-2-yl-amide hydrochloride

Parent CAS No.

[162760-96-5]

產(chǎn)品資料

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