| 產(chǎn)品名稱 | Torin 2 |
| 產(chǎn)品貨號(hào) | Axon 1834 CAS [1223001-51-1] MF C24H15F3N4OMW 432.40 Purity: 99% Soluble in DMSO Description Potent, selective, orally available and ATP-competitive mTOR inhibitor (IC50: 2.1 nM for mTORC1), which possesses an EC50 of 0.25 nM for inhibiting cellular mTOR activity and exhibited 800-fold selectivity over PI3K (EC50: 200 nM) and over 100-fold binding selectivity relative to 440 other protein kinases References Certificates Categories Extra info Q Liu et al. Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available (mTOR) inhibitor for treatment of cancer. J. Med. Chem. 2011, 54(5), 1473-1480. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology mTOR PI3K-Akt-mTOR EC 2.7.11.1 mTOR inhibitor Chemical name 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one Parent CAS No. [1223001-51-1] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
Torin 2Axon 1834 CAS [1223001-51-1] MF C24H15F3N4O
Description
Potent, selective, orally available and ATP-competitive mTOR inhibitor (IC50: 2.1 nM for mTORC1), which possesses an EC50 of 0.25 nM for inhibiting cellular mTOR activity and exhibited 800-fold selectivity over PI3K (EC50: 200 nM) and over 100-fold binding selectivity relative to 440 other protein kinases
mTOR inhibitor
Chemical name9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one Parent CAS No.[1223001-51-1] |
| 產(chǎn)品資料 |
