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產(chǎn)品名稱

AZD 8055

產(chǎn)品貨號(hào)

Axon 1561 CAS [1009298-09-2] MF C25H31N5O4MW 465.54 Purity: 99% Optical purity: Optically pure Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective mTOR inhibitor, with IC50 values to be 0.8 nM and selectivity ca 1000-fold against class I PI3K and other PIKKs References Certificates Categories Extra info CM Chresta et al. AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity. Cancer Res. 2010, 70(1), 288-298. ? P Sini et al. Simultaneous inhibition of mTORC1 and mTORC2 by mTOR kinase inhibitor AZD8055 induces autophagy and cell death in cancer cells. Autophagy. 2010, 6(4).? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell mTOR PI3K-Akt-mTOR EC 2.7.11.1 mTOR inhibitor Chemical name (5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Parent CAS No. [1009298-09-2] Order Size Unit Price Stock 5 mg €95.00 In Stock

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

AZD 8055

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1561

CAS [1009298-09-2]

MF C25H31N5O4
MW 465.54

Purity: 99%
Optical purity: Optically pure
Soluble in 0.1N HCl(aq) and DMSO

AZD 8055

Description

Potent and selective mTOR inhibitor, with IC50 values to be 0.8 nM and selectivity ca 1000-fold against class I PI3K and other PIKKs

CM Chresta et al. AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity. Cancer Res. 2010, 70(1), 288-298.

P Sini et al. Simultaneous inhibition of mTORC1 and mTORC2 by mTOR kinase inhibitor AZD8055 induces autophagy and cell death in cancer cells. Autophagy. 2010, 6(4).?

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Stem Cell mTOR PI3K-Akt-mTOR EC 2.7.11.1

mTOR inhibitor

Chemical name

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol

Parent CAS No.

[1009298-09-2]

產(chǎn)品資料

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