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產(chǎn)品名稱

KU 0063794 - KU 63794

產(chǎn)品貨號

Axon 1472 CAS [938440-64-3] MF C25H31N5O4MW 465.54 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective mTOR inhibitor, with IC50 values to be about 10 nM for mTORC1 and mTORC2. KEYWORDS: KU 0063794 | supplier | mTOR inhibitor | KU 63794 | KU0063794 | KU63794 | KU-0063794 | KU-63794 | CAS [938440-64-3] | Phosphatidylinositol | mTOR | Inhibitor | Enzymes

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

KU 0063794 - KU 63794

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1472

CAS [938440-64-3]

MF C25H31N5O4
MW 465.54

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

KU 0063794

Description

Potent and selective mTOR inhibitor, with IC50 values to be about 10 nM for mTORC1 and mTORC2.

KEYWORDS: KU 0063794 | supplier | mTOR inhibitor | KU 63794 | KU0063794 | KU63794 | KU-0063794 | KU-63794 | CAS [938440-64-3] | Phosphatidylinositol | mTOR | Inhibitor | Enzymes

J Garcia-Martinez et al. Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR). Biochem. J. 2009, 421, 29-42.?

K Garber. Targeting mTOR: Something Old, Something New.? J. Nat. Can. Inst 2009, 101(5),288-290.?

K Malagu et al. The discovery and optimisation of pyrido[2,3-d]pyrimidine-2,4-diamines as potent and selective inhibitors of mTOR kinase. Bioorg. Med. Chem. Lett. 2009, 19(20), 5950-5953.?

Certificate of Analysis
Material Safety Data Sheet

Cell Cycle Regulation Cell Signaling & Oncology Stem Cell mTOR PI3K-Akt-mTOR EC 2.7.11.1

mTOR inhibitor

Chemical name

{5-[2-((2S,6R)-2,6-Dimethyl-morpholin-4-yl)-4-morpholin-4-yl-pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-phenyl}-methanol

Parent CAS No.

[938440-64-3]

產(chǎn)品資料

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