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產(chǎn)品名稱

CHIR 98014 - CT 98014

產(chǎn)品貨號(hào)

Axon 1126 CAS [252935-94-7] MF C20H17Cl2N9O2MW 486.31 Purity: 98% Moderately soluble in DMSO Description Very potent, selective, cell-permeable reversible inhibitor of GSK-3; highly recommended tool. KEYWORDS:?CHIR 98014 | supplier | GSK-3 inhibitor | CT 98014 | CHIR98014 | CT98014 | CHIR-98014 | CT-98014 | CAS [252935-94-7] | ?glycogen synthase kinase | cell-permeable | reversible | CNS | Alzheimer | tau | phosphorylation | plaque

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

CHIR 98014 - CT 98014

Based on 132 reference(s) in Google Scholar 10 10 132

Axon 1126

CAS [252935-94-7]

MF C20H17Cl2N9O2
MW 486.31

Purity: 98%
Moderately soluble in DMSO

CHIR 98014

Description

Very potent, selective, cell-permeable reversible inhibitor of GSK-3; highly recommended tool.

KEYWORDS:?CHIR 98014 | supplier | GSK-3 inhibitor | CT 98014 | CHIR98014 | CT98014 | CHIR-98014 | CT-98014 | CAS [252935-94-7] | ?glycogen synthase kinase | cell-permeable | reversible | CNS | Alzheimer | tau | phosphorylation | plaque

ML Selenica et al. Efficacy of small-molecule glycogen synthase kinase-3 inhibitors in the postnatal rat model of tau hyperphosphorylation. Br. J. Pharmacol. 2007, 152, 959–979.?

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SE Nikoulina et al. Inhibition of Glycogen Synthase Kinase 3 Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle. Diabetes 2002, 51(7), 2190-2198.?

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DB Ring et al. Selective glycogen synthase kinase inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 2003,?52, 588–595.?

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AS Wagman et al. Discovery and development of GSK3 inhibitors for the treatment of type 2 diabetes. Curr. Pharm. Des. 2004, 10, 1105–1137.?

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List of publications utilizing CHIR 98014 - CT98014 (Axon 1126) purchased from Axon Medchem

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology CNS Diabetes & Metabolism Immunology Pain & Inflammation Stem Cell GSK-3 Wnt-β-Catenin PI3K-Akt-mTOR EC 2.7.11.26

GSK-3 inhibitor

Chemical name

N*6*-{2-[4-(2,4-Dichloro-phenyl)-5-imidazol-1-yl-pyrimidin-2-ylamino]-ethyl}-3-nitro-pyridine-2,6-diamine

Parent CAS No.

[252935-94-7]

產(chǎn)品資料

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