| 產(chǎn)品名稱 | LDN 193189 hydrochloride - DM 3189 hydrochloride | |||
| 產(chǎn)品貨號(hào) | Axon 1509 CAS [1435934-00-1] MF C25H22N6.2HClMW 479.40 Purity: 99% Soluble in water and DMSO Description A highly potent small molecule BMP inhibitor; inhibiting BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation; useful tool in stem cell biology.?LDN 193189 shows significant in vivo clinical utility, inhibiting FOP and ectopic ossification and a potential agent in the treatment of NSCLC lung tumors. *Promotion | |||
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 | |||
| 產(chǎn)品規(guī)格 | ||||
| 產(chǎn)品品牌 | axonmedchem | |||
| 產(chǎn)品概述 | ||||
| 產(chǎn)品詳情 |
LDN 193189 hydrochloride - DM 3189 hydrochlorideAxon 1509 CAS [1435934-00-1] MF C25H22N6.2HCl
DescriptionA highly potent small molecule BMP inhibitor; inhibiting BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation; useful tool in stem cell biology.?LDN 193189 shows significant in vivo clinical utility, inhibiting FOP and ectopic ossification and a potential agent in the treatment of NSCLC lung tumors. *Promotion: LDN 193189 HCl is also part of Inhibitor Set(s):
KEYWORDS:?LDN 193189 hydrochloride | supplier | BMP inhibitor | DM 3189 HCl | LDN193189 | DM3189 | CAS [1435934-00-1] | [1062368-24-4] | [1062368-62-0] | TGF-β | BMP-ALK | Antagonist | RSTK | ALK2 | ALK3 | ALK6 | SMAD | stem cell biology | FOP | ectopic ossification | NSCLC ? List of publications using LDN 193189 (Axon 1509) purchased from Axon Medchem
Highly potent small molecule inhibitor of BMP type I receptors ALK2, ALK3, and ALK6
Chemical name4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline hydrochloride Parent CAS No.[1062368-24-4] |
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| 產(chǎn)品資料 |
