| 產(chǎn)品名稱(chēng) | EGFR Inhibitor [879127-07-8] - EGFR Inhibitor 324674 |
| 產(chǎn)品貨號(hào) | Axon 1760 CAS [879127-07-8] MF C21H18F3N5OMW 413.40 Purity: 99% Soluble in DMSO Description A potent, cell permeable, irreversible and highly selective EGFR tyrosine kinase inhibitor with IC50 value in the nM range References Certificates Categories Extra info Q Zhang et al. Discovery of EGFR selective 4,6-disubstituted pyrimidines from a combinatorial kinase-directed heterocycle library. J. Am. Chem. Soc. 2006, 128(7), 2182-2183. ? K Okamoto et al. Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations. Cancer Res. 2010, 70(24), 10402-10410. ? Z Yu et al. Novel irreversible EGFR tyrosine kinase inhibitor 324674 sensitizes human colon carcinoma HT29 and SW480 cells to apoptosis by blocking the EGFR pathway. Biochem. Biophys. Res. Commun. 2011, 411(4), 751-756. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology EGFR JAK-STAT RTK class I; EC 2.7.10.1 Highly selective EGFR tyrosine kinase inhibitor Chemical name N-(3-(6-(3-(trifluoromethyl)phenylamino)pyrimidin-4-ylamino)phenyl)cyclopropanecarboxamide Parent CAS No. [879127-07-8] Order Size Unit Price Stock 5 mg €125.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
EGFR Inhibitor [879127-07-8] - EGFR Inhibitor 324674Axon 1760 CAS [879127-07-8] MF C21H18F3N5O
Description
A potent, cell permeable, irreversible and highly selective EGFR tyrosine kinase inhibitor with IC50 value in the nM range
Highly selective EGFR tyrosine kinase inhibitor
Chemical nameN-(3-(6-(3-(trifluoromethyl)phenylamino)pyrimidin-4-ylamino)phenyl)cyclopropanecarboxamide Parent CAS No.[879127-07-8] |
| 產(chǎn)品資料 |
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