| 產(chǎn)品名稱 | VU 0238429 |
| 產(chǎn)品貨號 | Axon 1786 CAS [1160247-92-6] MF C17H12F3NO4MW 351.28 Purity: 99% Soluble in DMSO and Ethanol Description Highly selective positive allosteric modulator (PAM) of M5 muscarinic acetylcholine receptor (mAChR) References Certificates Categories Extra info TM Bridges et al. Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins. J. Med. Chem. 2009,?52(11), 3445–3448.? ? PJ Conn?et al.??Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders. Trends Pharmacol. Sci. 2009,?30(3), 148–155.? ? TM Bridges et al. Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators. Bioorg. Med. Chem. Lett. 2010,?20(19), 5617. Certificate of Analysis Material Safety Data Sheet CNS CHRM5 A18 Selective PAM of M5 mAChR (CHRM5) Chemical name 1-(4-methoxybenzyl)-5-(trifluoromethoxy)indoline-2,3-dione Parent CAS No. [1160247-92-6] Order Size Unit Price Stock 10 mg €105.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
VU 0238429Axon 1786 CAS [1160247-92-6] MF C17H12F3NO4
Description
Highly selective positive allosteric modulator (PAM) of M5 muscarinic acetylcholine receptor (mAChR)
Selective PAM of M5 mAChR (CHRM5)
Chemical name1-(4-methoxybenzyl)-5-(trifluoromethoxy)indoline-2,3-dione Parent CAS No.[1160247-92-6] |
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