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產品名稱

FK 866 hydrochloride - K 22.175 hydrochloride

產品貨號

Axon 1546 CAS [658084-64-1] MF C24H29N3O2.HClMW 427.97 Purity: 99% Soluble in water and DMSO Description Highly specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT); NAD biosysthesis inhibitor; Tumor cell apoptosis agent (see also Axon 1279) References Certificates Categories Extra info M. Hasmann and I. Schemainda, FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res. 2003, 63, 7436-7442. ? A Pogrebniak et al. Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents. Eur. J. Med. Res. 2006, 11(8), 313-321. ? K Holen et al. The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor. Invest. New Drugs. 2008, 26(1), 45-51.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Diabetes & Metabolism NAMPT EC 2.4.2.12 NAMPT inhibitor Chemical name (E)-N-[4-(1-Benzoyl-piperidin-4-yl)-butyl]-3-pyridin-3-yl-acrylamide hydrochloride Parent CAS No. [658084-64-1] Order Size Unit Price Stock 5 mg €90.00 In Stock

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

產品品牌

axonmedchem

產品概述

產品詳情

FK 866 hydrochloride - K 22.175 hydrochloride

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1546

CAS [658084-64-1]

MF C24H29N3O2.HCl
MW 427.97

Purity: 99%
Soluble in water and DMSO

FK 866 hydrochloride

Description

Highly specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT); NAD biosysthesis inhibitor; Tumor cell apoptosis agent (see also Axon 1279)

M. Hasmann and I. Schemainda, FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res. 2003, 63, 7436-7442.

A Pogrebniak et al. Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents. Eur. J. Med. Res. 2006, 11(8), 313-321.

K Holen et al. The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor. Invest. New Drugs. 2008, 26(1), 45-51.?

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Signaling & Oncology Diabetes & Metabolism NAMPT EC 2.4.2.12

NAMPT inhibitor

Chemical name

(E)-N-[4-(1-Benzoyl-piperidin-4-yl)-butyl]-3-pyridin-3-yl-acrylamide hydrochloride

Parent CAS No.

[658084-64-1]

產品資料

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