| 產(chǎn)品名稱 | SMI 4a - Pim inhibitor 4a |
| 產(chǎn)品貨號 | Axon 1923 CAS [438190-29-5] MF C11H6F3NO2SMW 273.23 Purity: 98% Soluble in DMSO Description ATP-competitive and selective inhibitor of Pim kinases, with IC50 values of 24 and 100 nM for Pim-1 and Pim-2 respectively. SMI-4a inhibits prostate cancer cell growth and induce G1 phase cell-cycle arrest in precursor T-cell lymphoblastic leukemia/lymphoma cell lines References Certificates Categories Extra info Z Xia et al. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J. Med. Chem. 2009, 52(1), 74-86.? ? YW Lin et al. A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. Blood. 2010, 115(4), 824-833.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics Immunology JAK-STAT EC 2.7.11.1 PIM ATP-competitive and selective inhibitor of Pim kinases Chemical name (Z)-5-(3-(trifluoromethyl)benzylidene)thiazolidine-2,4-dione Parent CAS No. [438190-29-5] Order Size Unit Price Stock 10 mg €75.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
SMI 4a - Pim inhibitor 4aAxon 1923 CAS [438190-29-5] MF C11H6F3NO2S
Description
ATP-competitive and selective inhibitor of Pim kinases, with IC50 values of 24 and 100 nM for Pim-1 and Pim-2 respectively. SMI-4a inhibits prostate cancer cell growth and induce G1 phase cell-cycle arrest in precursor T-cell lymphoblastic leukemia/lymphoma cell lines
ATP-competitive and selective inhibitor of Pim kinases
Chemical name(Z)-5-(3-(trifluoromethyl)benzylidene)thiazolidine-2,4-dione Parent CAS No.[438190-29-5] |
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