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產(chǎn)品名稱

CAIX Inhibitor S4

產(chǎn)品貨號(hào)

Axon 2662 CAS [1330061-67-0] MF C15H17N3O4SMW 335.38 Purity: 99% Soluble in DMSO Description S4 is a carbonic anhydrase (CA) IX and XII inhibitor (Ki values 7 nM and 2 nM, respectively) and showed a positive response in in vitro assays for tumor cell migration and spreading. Moreover, CAIX inhibitor S4 effectively inhibited the spontaneous metastasis formation in MDA-MB-231 xenografts.

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

CAIX Inhibitor S4

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2662

CAS [1330061-67-0]

MF C15H17N3O4S
MW 335.38

Purity: 99%
Soluble in DMSO

CAIX Inhibitor S4

Description

S4 is a carbonic anhydrase (CA) IX and XII inhibitor (Ki values 7 nM and 2 nM, respectively) and showed a positive response in in vitro assays for tumor cell migration and spreading. Moreover, CAIX inhibitor S4 effectively inhibited the spontaneous metastasis formation in MDA-MB-231 xenografts.

RG Gieling et al. Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts. J Med Chem. 2012 Jun 14;55(11):5591-600.

Certificate of Analysis
Material Safety Data Sheet

Cardiovascular Cell Signaling & Oncology Diabetes & Metabolism Miscellaneous Carbonic Anhydrase EC 4.2.1.1

Carbonic anhydrase (CA) IX/XII inhibitor

Chemical name

4-(3-(3,5-Dimethylphenyl)ureido)phenyl sulfamate

Parent CAS No.

[1330061-67-0]

產(chǎn)品資料

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