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產(chǎn)品名稱

cPEPCK inhibitor

產(chǎn)品貨號(hào)

Axon 1165 CAS [628279-07-2] MF C25H26FN5O3MW 463.50 Purity: 98% Soluble in DMSO Description The first GTP-competitive inhibitor of human cytosolic phosphoenolpyruvate carboxykinase (PEPCK or cPEPCK) with low submicromolar IC50 values. KEYWORDS:?cPEPCK inhibitor | supplier | cPEPCK inhibitor | CAS [628279-07-2] | Gluconeogenesis | PEPCK | GTP-competitive | human | cytosolic | phosphoenolpyruvate carboxykinase | glucose homeostasis | Type 2 | diabetes

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

cPEPCK inhibitor

Based on 5 publications in PubMed 9 10 5

Axon 1165

CAS [628279-07-2]

MF C25H26FN5O3
MW 463.50

Purity: 98%
Soluble in DMSO

cPEPCK inhibitor

Description

The first GTP-competitive inhibitor of human cytosolic phosphoenolpyruvate carboxykinase (PEPCK or cPEPCK) with low submicromolar IC50 values.

KEYWORDS:?cPEPCK inhibitor | supplier | cPEPCK inhibitor | CAS [628279-07-2] | Gluconeogenesis | PEPCK | GTP-competitive | human | cytosolic | phosphoenolpyruvate carboxykinase | glucose homeostasis | Type 2 | diabetes

LH Foley et al. Modified 3-alkyl-1,8-dibenzylxanthines as GTP-competitive inhibitors of phosphoenolpyruvate carboxykinase. Bioorg. Med. Chem. Lett. 2003, 13(20), 3607-10.?

?

LH Foley et al. X-ray structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-dibenzylxanthines. Bioorg. Med. Chem. Lett. 2003, 13(21), 3871-4.?

?

SL Pietranico et al. C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase. Bioorg. Med. Chem. Lett. 2007, 17(14), 3835-9.?

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Diabetes & Metabolism Miscellaneous PEPCK EC 4.1.1.32

cPEPCK inhibitor

Chemical name

N-{4-[3-Butyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,9-tetrahydro-1H-purin-8-ylmethyl]-phenyl}-acetamide

Parent CAS No.

[628279-07-2]

產(chǎn)品資料

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