| 產(chǎn)品名稱 | LH 846 |
| 產(chǎn)品貨號 | Axon 2297 CAS [639052-78-1] MF C16H13ClN2OSMW 316.81 Purity: 99% Soluble in DMSO Description Potent and selective inhibitor of CK1δ ( IC50 values of 2.5 mM, 290 nM, and 1.3 mM for CK1α, CK1δ, and CK1ε, respectively) that showed no inhibitory effect on CK2. LH 846 modulates circadian rhythms through phosphorylation of the period protein with a significant effect on circadian period length (10 h) with minimal effect on the amplitude of both Per2-dLuc and Bmal1-dLuc rhythms in U2OS cells. References Certificates Categories Extra info J.W. Lee et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew. Chem. Int. Ed. Engl. 2011, 50, 10608-10611. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell Wnt-β-Catenin EC 2.7.11.1 CK Inhibitor of Casein kinase 1 (CK1δ) Chemical name N-(5-chloro-6-methylbenzo[d]thiazol-2-yl)-2-phenylacetamide Parent CAS No. [639052-78-1] Order Size Unit Price Stock 10 mg €95.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
LH 846Axon 2297 CAS [639052-78-1] MF C16H13ClN2OS
Description
Potent and selective inhibitor of CK1δ ( IC50 values of 2.5 mM, 290 nM, and 1.3 mM for CK1α, CK1δ, and CK1ε, respectively) that showed no inhibitory effect on CK2. LH 846 modulates circadian rhythms through phosphorylation of the period protein with a significant effect on circadian period length (10 h) with minimal effect on the amplitude of both Per2-dLuc and Bmal1-dLuc rhythms in U2OS cells.
Inhibitor of Casein kinase 1 (CK1δ)
Chemical nameN-(5-chloro-6-methylbenzo[d]thiazol-2-yl)-2-phenylacetamide Parent CAS No.[639052-78-1] |
| 產(chǎn)品資料 |
