| 產(chǎn)品名稱 | CK2 inhibitor 10 |
| 產(chǎn)品貨號 | Axon 2202 CAS [1361229-76-6] MF C18H14N2O4SMW 354.38 Purity: 99% Soluble in DMSO Description Potent and ATP-competitive inhibitor of protein kinase (CK2; IC50 values of 32 nM and 46 nM for CK2α and CK2α' respectively). At 0.30 μM, compound 10 exhibited a >50% inhibitory effect against 9 out of 70 other kinases besides CK2α and CK2α′, while at 30 nM >75% inhibition was observed for two other kinases (DYRK1B and FLT3) only. It exhibited potent cytotoxicity towards lung cancer cells A549, colorectal cancer cells HCT-116, and breast cancer cells MCF-7. References Certificates Categories Extra info Z. Hou et al. Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds. J. Med. Chem. 2012, 55, 2899-2903. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell Wnt-β-Catenin EC 2.7.11.1 CK Potent and ATP-competitive inhibitor of CK2 Chemical name 4-(2-(4-methoxybenzamido)thiazol-5-yl)benzoic acid Parent CAS No. [1361229-76-6] Order Size Unit Price Stock 10 mg €105.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
CK2 inhibitor 10Axon 2202 CAS [1361229-76-6] MF C18H14N2O4S
Description
Potent and ATP-competitive inhibitor of protein kinase (CK2; IC50 values of 32 nM and 46 nM for CK2α and CK2α' respectively). At 0.30 μM, compound 10 exhibited a >50% inhibitory effect against 9 out of 70 other kinases besides CK2α and CK2α′, while at 30 nM >75% inhibition was observed for two other kinases (DYRK1B and FLT3) only. It exhibited potent cytotoxicity towards lung cancer cells A549, colorectal cancer cells HCT-116, and breast cancer cells MCF-7.
Potent and ATP-competitive inhibitor of CK2
Chemical name4-(2-(4-methoxybenzamido)thiazol-5-yl)benzoic acid Parent CAS No.[1361229-76-6] |
| 產(chǎn)品資料 |
