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產(chǎn)品名稱

EN460 - ERO1 Inhibitor II

產(chǎn)品貨號

Axon 2737 CAS [496807-64-8] MF C22H12ClF3N2O4MW 460.79 Purity: 99% Soluble in DMSO Description EN460, an inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation (IC50 value of 1.9 μM). Despite rapid and promiscuous reactivity with thiolates, EN460 exhibits selectivity for ERO1. KEYWORDS: EN460 | supplier | ERO1 inhibitor | ERO1 Inhibitor II | EN 460 | EN-460 | CAS [496807-64-8] | Protein Disulfide Isomerase (PDI) | ERO1 | Inhibitor | Enzymes | Endoplasmic Reticulum Oxidation

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

EN460 - ERO1 Inhibitor II

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2737

CAS [496807-64-8]

MF C22H12ClF3N2O4
MW 460.79

Purity: 99%
Soluble in DMSO

EN460

Description

EN460, an inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation (IC50 value of 1.9 μM). Despite rapid and promiscuous reactivity with thiolates, EN460 exhibits selectivity for ERO1.

JD Blais et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J Biol Chem. 2010 Jul 2;285(27):20993-1003.

Certificate of Analysis
Material Safety Data Sheet

Epigenetics Miscellaneous ERO1

Inhibitor of endoplasmic reticulum oxidation 1 (ERO1)

Chemical name

(Z)-2-Chloro-5-(5-oxo-4-((5-phenylfuran-2-yl)methylene)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid

Parent CAS No.

[496807-64-8]

產(chǎn)品資料

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