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產(chǎn)品名稱

GSK837149

產(chǎn)品貨號

Axon 2617 CAS [13616-29-0] MF C23H22N8O5S2MW 554.60 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Selective inhibitor of human fatty acid synthase (FAS; Ki value 30 nM) that acts by inhibition the β-ketoacyl reductase activity of the enzyme. KEYWORDS:?GSK837149 | supplier | FAS inhibitor | GSK 837149A | GSK-837149A | CAS [13616-29-0] | Fatty acid synthase | FASN | lipids | beta-ketoacyl reductase | KR | CoA | prostate | ovarian | cancer | carcinoma | obesity

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

GSK837149

Based on 3 reference(s) in Google Scholar 9 10 3

Axon 2617

CAS [13616-29-0]

MF C23H22N8O5S2
MW 554.60

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

GSK837149

Description

Selective inhibitor of human fatty acid synthase (FAS; Ki value 30 nM) that acts by inhibition the β-ketoacyl reductase activity of the enzyme.

KEYWORDS:?GSK837149 | supplier | FAS inhibitor | GSK 837149A | GSK-837149A | CAS [13616-29-0] | Fatty acid synthase | FASN | lipids | beta-ketoacyl reductase | KR | CoA | prostate | ovarian | cancer | carcinoma | obesity

MJ Vázquez et al. Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the beta-ketoacyl reductase reaction. FEBS J. 2008 Apr;275(7):1556-67.

?

R Flavin et al. Fatty acid synthase as a potential therapeutic target in cancer. Future Oncol. 2010 Apr;6(4):551-62.

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Diabetes & Metabolism Endocrinology FAS EC 3.2.1.85

Selective inhibitor of human fatty acid synthase (FAS)

Chemical name

4,4'-carbonylbis(azanediyl)bis(N-(4-methylpyrimidin-2-yl)benzenesulfonamide)

Parent CAS No.

[13616-29-0]

產(chǎn)品資料

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