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產(chǎn)品名稱

STX64 - BN83495 | Irosustat | 667 Coumate

產(chǎn)品貨號

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

STX64 - BN83495 | Irosustat | 667 Coumate

Based on 123 reference(s) in Google Scholar 8 10 123

Axon 2892

CAS [288628-05-7]

MF C14H15NO5S
MW 309.34

Purity: 99%
Soluble in DMSO

STX64

Description

Potent steroid sulfatase (STS) inhibitor with an IC50 value of 8 nM. First STS inhibitor to enter diverse clinical trials for patients with advanced hormone-dependent cancer.

A Purohit et al. In vivo inhibition of estrone sulfatase activity and growth of nitrosomethylurea-induced mammary tumors by 667 COUMATE. Cancer Res. 2000 Jul 1;60(13):3394-6.

LW Woo et al. Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495). ChemMedChem. 2011 Nov 4;6(11):2019-34.

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Endocrinology Sulfatases EC 3.1.6.2

Potent steroid sulfatase (STS) inhibitor

Chemical name

6-Oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate

Parent CAS No.

[288628-05-7]

產(chǎn)品資料

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