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產(chǎn)品名稱

WNK Inhibitor 11

產(chǎn)品貨號(hào)

Axon 2896 CAS [2123489-30-3] MF C21H21Cl2N5OSMW 462.40 Purity: 98% Soluble in DMSO Description Selective allosteric WNK1 inhibitor (IC50 value of 0.004 μM) with nearly 1000-fold selectivity for WNK1 vs WNK4 and 57-fold selectivity for WNK1 vs WNK2. Keywords: WNK Inhibitor 11 | supplier | WNK1 inhibitor? | CAS [2123489-30-3] | Cation-Cl? cotransporters (CCCs) | WNK | Inhibitor | Enzymes | Hypertension

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

WNK Inhibitor 11

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2896

CAS [2123489-30-3]

MF C21H21Cl2N5OS
MW 462.40

Purity: 98%
Soluble in DMSO

WNK Inhibitor 11

Description

Selective allosteric WNK1 inhibitor (IC50 value of 0.004 μM) with nearly 1000-fold selectivity for WNK1 vs WNK4 and 57-fold selectivity for WNK1 vs WNK2.

K Yamada et al. Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. J Med Chem. 2017 Aug 24;60(16):7099-7107.

Certificate of Analysis
Material Safety Data Sheet

Cardiovascular EC 2.7.11.1 WNK

Selective allosteric inhibitor of WNK1

Chemical name

(5-Chloro-2-(2-(methylamino)thiazol-4-yl)pyridin-4-yl)(4-(4-chlorobenzyl)piperazin-1-yl)methanone

Parent CAS No.

[2123489-30-3]

產(chǎn)品資料

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