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產(chǎn)品名稱

BAN ORL 24 dihydrochloride

產(chǎn)品貨號

Axon 1784 CAS [1401463-54-4] MF C27H35N3O2.2HClMW 506.51 Purity: 99% Optical purity: Optically pure Soluble in water, DMSO, and Ethanol Description Highly potent and selective NOP receptor antagonist (IC50: 0.27 nM); more than 2500 fold selective over other opioid receptors KEYWORDS: BAN ORL 24 | supplier | NOP antagonist | 1401463-54-4 | 475150-69-7 | BANORL24 | BAN-ORL-24 | Opioid | nociceptin | OPR (NOP) | Orphanin | dopamine | D2

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

BAN ORL 24 dihydrochloride

Based on 38 publications in PubMed 10 10 38

Axon 1784

CAS [1401463-54-4]

MF C27H35N3O2.2HCl
MW 506.51

Purity: 99%
Optical purity: Optically pure
Soluble in water, DMSO, and Ethanol

BAN ORL 24 dihydrochloride

Description

Highly potent and selective NOP receptor antagonist (IC50: 0.27 nM); more than 2500 fold selective over other opioid receptors

KEYWORDS: BAN ORL 24 | supplier | NOP antagonist | 1401463-54-4 | 475150-69-7 | BANORL24 | BAN-ORL-24 | Opioid | nociceptin | OPR (NOP) | Orphanin | dopamine | D2

Y Goto et al. Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity. J. Med. Chem. 2006,?49 847-849.?

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C Fischetti et al. Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist compound 24. Eur. J. Pharmacol. 2009,?614 50-57.?

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Y Liao et al. 1-Benzyl-N-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl]pyrrolidine-2-carboxamide (compound 24) antagonizes NOP receptor-mediated potassium channel activation in rat periaqueductal gray slices. Eur. J. Pharmacol. 2009, 606 84-89.?

Certificate of Analysis
Material Safety Data Sheet

CNS Pain & Inflammation Endocrinology OPR (NOP) A4

NOP receptor antagonist

Chemical name

(R)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-1-benzylpyrrolidine-2-carboxamide dihydrochloride

Parent CAS No.

[475150-69-7]

產(chǎn)品資料

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