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產(chǎn)品名稱

PNU 282987 hydrochloride

產(chǎn)品貨號

Axon 2908 CAS [123464-89-1] MF C14H17ClN2O.HClMW 301.21 Purity: 99% Optical purity: Optically pure Soluble in water and DMSO Description PNU 282987 hydrochloride is an α7 nicotinic acetylcholine receptor (nAChR) agonist with Ki (α7 nAChR) and EC50 (α7-5HT3 chimera) values of 27 nm and 154 nM, respectively. PNU 282987 hydrochloride

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

PNU 282987 hydrochloride

Based on 140 reference(s) in Google Scholar 8 10 140

Axon 2908

CAS [123464-89-1]

MF C14H17ClN2O.HCl
MW 301.21

Purity: 99%
Optical purity: Optically pure
Soluble in water and DMSO

PNU 282987 hydrochloride

Description

PNU 282987 hydrochloride is an α7 nicotinic acetylcholine receptor (nAChR) agonist with Ki (α7 nAChR) and EC50 (α7-5HT3 chimera) values of 27 nm and 154 nM, respectively. PNU 282987 hydrochloride?was also shown to open native α7 nAChRs in cultured rat neurons and to reverse an amphetamine-induced gating deficit in rats.

AL Bodnar et al. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem. 2005 Feb 24;48(4):905-8.

Certificate of Analysis
Material Safety Data Sheet

CNS Pain & Inflammation nAChR Unclassified

nAChR agonist (α7 sub-unit selective)

Chemical name

(R)-4-Chloro-N-(quinuclidin-3-yl)benzamide hydrochloride

Parent CAS No.

[711085-63-1]

產(chǎn)品資料

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