| 產(chǎn)品名稱 | C-DIM12 - DIM-C-pPhCl |
| 產(chǎn)品貨號 | Axon 2575 CAS [178946-89-9] MF C23H17ClN2MW 356.85 Purity: 99% Soluble in DMSO Description Potent and specific Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters. C-DIM12 protects against loss of dopamine neurons in the substantia nigra as well as dopamine terminals in the striatum in MPTP-induced mouse models for Parkinson's disease. KEYWORDS: C-DIM12 | supplier | Nurr1 activator | DIM-C-pPhCl | CDIM12 | C-DIM 12 | CAS [178946-89-9] | Intracellular Transcription Factors | NURR | Activator | Nuclear Receptors | NR4A2 | inflammation | CNS | dopaminergic | neurons | NF-κB | ganglia | Parkinson's |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
C-DIM12 - DIM-C-pPhClAxon 2575 CAS [178946-89-9] MF C23H17ClN2
DescriptionPotent and specific Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters. C-DIM12 protects against loss of dopamine neurons in the substantia nigra as well as dopamine terminals in the striatum in MPTP-induced mouse models for Parkinson's disease. KEYWORDS: C-DIM12 | supplier | Nurr1 activator | DIM-C-pPhCl | CDIM12 | C-DIM 12 | CAS [178946-89-9] | Intracellular Transcription Factors | NURR | Activator | Nuclear Receptors | NR4A2 | inflammation | CNS | dopaminergic | neurons | NF-κB | ganglia | Parkinson's
Nurr1 activator that stimulates apoptosis in bladder cancer cells
Chemical name3,3'-((4-chlorophenyl)methylene)bis(1H-indole) Parent CAS No.[178946-89-9] |
| 產(chǎn)品資料 |
