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產(chǎn)品名稱

AZ-GHS-22

產(chǎn)品貨號

Axon 2340 CAS [1143020-91-0] MF C27H33ClN6O5S2MW 621.17 Purity: 98% Soluble in 0.1N HCl(aq) and DMSO Description Orally available high affinity Ghrelin receptor (GHS-R1a) inverse agonist (IC50 0.77 nM) with very low CNS exposure. KEYWORDS: AZ-GHS-22 | supplier | GHS-R1a inverse agonist | AZGHS22 | CAS [1143020-91-0] | Metabolism | GHSR | Inverse agonist | Ghrelin | CNS | food | intake | metabolism | brain penetrant

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

AZ-GHS-22

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2340

CAS [1143020-91-0]

MF C27H33ClN6O5S2
MW 621.17

Purity: 98%
Soluble in 0.1N HCl(aq) and DMSO

AZ-GHS-22

Description

Orally available high affinity Ghrelin receptor (GHS-R1a) inverse agonist (IC50 0.77 nM) with very low CNS exposure.

KEYWORDS: AZ-GHS-22 | supplier | GHS-R1a inverse agonist | AZGHS22 | CAS [1143020-91-0] | Metabolism | GHSR | Inverse agonist | Ghrelin | CNS | food | intake | metabolism | brain penetrant

W. McCoull et al. Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonists. J Med Chem. 2014 Jul 24;57(14):6128-40. doi: 10.1021/jm500610n. Epub 2014 Jul 8.

Certificate of Analysis
Material Safety Data Sheet

CNS Diabetes & Metabolism Endocrinology A7 Ghrelin (GHSR)

Orally available Ghrelin receptor (GHS-R1a) inverse agonist

Chemical name

2-chloro-N-(6-(3-(4-methylpiperazin-1-yl)propylsulfonyl)benzo[d]thiazol-2-ylcarbamoyl)-5-morpholinobenzamide

Parent CAS No.

[1143020-91-0]

產(chǎn)品資料

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