<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱

Org OD 02-0 - 19-CH2P4

產(chǎn)品貨號

Axon 2085 CAS [13258-85-0] MF C22H30O2MW 326.47 Purity: 100% Optical purity: Optically pure Soluble in DMSO Description Selective agonist of membrane progesterone receptor (mPR; IC50 value 33.9 nM). Org OD 02-0 mimics the protective effects of progestin hormones on serum starvation-induced cell death and apoptosis in both granulosa and breast cancer cells without altering caspase 3 activity. Org OD 02-0 significantly increased mitochondrial membrane potential (MMP) in serum starved MB468 cells. KEYWORDS: Org OD 02-0 | supplier | mPR agonist | 19-CH2P4 | OrgOD02-0 | 19-CH2P4 | CAS [13258-85-0] | Progesterone | Progesterone (mPR) | Agonist | Receptors | Progestin | membrane | adipoQ | PAQR

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Org OD 02-0 - 19-CH2P4

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2085

CAS [13258-85-0]

MF C22H30O2
MW 326.47

Purity: 100%
Optical purity: Optically pure
Soluble in DMSO

Org OD 02-0

Description

Selective agonist of membrane progesterone receptor (mPR; IC50 value 33.9 nM). Org OD 02-0 mimics the protective effects of progestin hormones on serum starvation-induced cell death and apoptosis in both granulosa and breast cancer cells without altering caspase 3 activity. Org OD 02-0 significantly increased mitochondrial membrane potential (MMP) in serum starved MB468 cells.

J. Kelder et al. Comparison between steroid binding to membrane progesterone receptor alpha (mPRalpha) and to nuclear progesterone receptor: correlation with physicochemical properties assessed by comparative (...). Steroids. 2010, 75, 314-322.?

G.E. Dressing et al. Membrane progesterone receptors (mPRs) mediate progestin induced antimorbidity in breast cancer cells and are expressed in human breast tumors. Horm. Cancer. 2012, 3, 101-112.?

P. Thomas et al. Membrane progesterone receptors: evidence for neuroprotective, neurosteroid signaling and neuroendocrine functions in neuronal cells. Neuroendocrinology. 2012, 96, 162-171.?

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Progesterone (mPR) Endocrinology MAPK PI3K-Akt-mTOR PAQR7

Selective agonist of membrane progesterone receptor (mPR)

Chemical name

(8S,9S,10S,13S,14S,17S)-17-acetyl-13-methyl-10-vinyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Parent CAS No.

[13258-85-0]

產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>