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產(chǎn)品名稱

ML 221

產(chǎn)品貨號

Axon 2870 CAS [877636-42-5] MF C17H11N3O6SMW 385.35 Purity: 99% Soluble in DMSO Description Potent apelin (APJ) receptor functional antagonist in cell-based assays (IC50 value is 1.75 μM). ML 221 is >37-fold selective over the closely related angiotensin II type 1 (AT-1) receptor. KEYWORDS: ML 221 | supplier | APJ antagonist? | ML221 | ML-221 | CAS [877636-42-5] | Apelin | Apelin (APJ) | Antagonist | Receptors

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

ML 221

Based on 8 reference(s) in Google Scholar 8 10 8

Axon 2870

CAS [877636-42-5]

MF C17H11N3O6S
MW 385.35

Purity: 99%
Soluble in DMSO

ML 221

Description

Potent apelin (APJ) receptor functional antagonist in cell-based assays (IC50 value is 1.75 μM). ML 221 is >37-fold selective over the closely related angiotensin II type 1 (AT-1) receptor.

KEYWORDS: ML 221 | supplier | APJ antagonist? | ML221 | ML-221 | CAS [877636-42-5] | Apelin | Apelin (APJ) | Antagonist | Receptors

PR Maloney et al. Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6656-60.

Certificate of Analysis
Material Safety Data Sheet

Cardiovascular Diabetes & Metabolism Apelin (APJ) A

Apelin receptor (APJ) antagonist

Chemical name

4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate

Parent CAS No.

[877636-42-5]

產(chǎn)品資料

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